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Profile:Manufacturer - Producer|Ref:PSL148165YH | Country: China | Currency: | Export: No
Artemisinin (qinghaosu) is the antimalarial principle isolated by Chinese scientists from Artemisia annua L. It is a sesquiterpene lactone with a peroxide bridge linkage. Artemisinin is poorly soluble in oils or water but the parent compound has yielded dihydroartemisinin, the oil-soluble derivatives artemether and arteether, and the more water-soluble derivatives sodium artesunate and artelinic acid. These derivatives have more potent blood schizonticidal activity than the parent compound and are the most rapidly effective antimalarial drugs known. They are used for the treatment of severe and uncomplicated malaria. They are not hypnozoiticidal but gametocytocidal activity has been observed.The antimalarial activity of artemisinin and its derivatives is extremely rapid and most patients show clinical improvement within 1-3 days after treatment.
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