Product or Service
Profile:Manufacturer - Producer|Ref:PSL2488YH | Country: China | Export: No
Irinotecan is a water soluble, semi-synthetic analogue of 20(S) camptothecin (CPT) with promising activity against
a range of tumour types. Irinotecan causes cell toxicity by stabilizing a ternary complex between the nuclear enzyme
topoisomerase I (topo I) and double-stranded DNA, leading to single and double strand breaks.
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