Minoxidil
Synonyms: 2,3-dihydro-3-hydroxy-2-imino-6-(1-piperidinyl)-4-pyrimidinamine;2,4-diamino-6-piperidinilpirimidina-3-ossido;2,4-diamino-6-piperidino-pyrimidin3-oxide;2,4-diamino-6-piperidinopyrimidine3-n-oxide;4-pyrimidinediamine,6-(1-piperidinyl)-3-oxide;6-amino-1,2-dihydro-1-hydroxy-2-imino-4-piperidinopyrimidine;6-piperidino-2,4-diaminopyrimidine3-oxide;alopexil
CAS: 38304-91-5
MF: C9H15N5O
MW: 209.25
EINECS: 253-874-2
Assay: 99%
Appearance: White or almost white crystalline powder
Chemical Property: Dissolved in glacial acetic acid, slightly soluble in ethanol, slightly soluble in chloroform or water, very slightly soluble in acetone. Odorless.
Usage:
Minoxidil is a vasodilator to treat hypertension, but the treatment of hair loss mechanism, is not primarily a vascular dilation function. According to the experimental study, the cultured hair follicle in vitro, adding minoxidil can increase the training time of hair follicle growth. Hair follicle of hepatocyte growth factor and vascular endothelial cell growth factor are the two main growth factor of hair papilla, have an important role in the regulation of hair growth cycle. Lachger et al reported minoxidil dermal papilla cells can be regulated vascular endothelial cell growth factor mRNA. So that minoxidil stimulated by these cytokines, hair follicle growth and extend the anagen phase, the miniaturization of the hair follicle development and promote the increase of dermal papilla blood vessel formation and function, and play an important role in the treatment of alopecia.
Packing: 25kg/drum
